Oral fungicides may lead to loss of pregnancy

Sábado, 09 Enero 2016 06:53
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Pregnant women have a higher risk of developing the yeast infection vaginal candidiasis due to an increased secretion of sex hormones; in the US, around 10% of pregnant women develop the condition.

Although intravaginal formulations of topical azole antifungals are the first-line treatment for pregnant women, oral fluconazole is often used.

However, there is a lack of safety information for the drug; in addition, previous studies have suggested evidence of a distinct pattern of craniofacial and skeletal birth defects in babies born to women treated long term with high-dose fluconazole during pregnancy.

Ditte Mølgaard-Nielsen, of the Statens Serum Institut in Copenhagen, Denmark, and colleagues evaluated the association between oral fluconazole exposure during pregnancy and the risk of spontaneous abortion and stillbirth.

In a nationwide cohort study, the team studied 1,405,663 pregnancies from 1997-2013 in Denmark.

Read 258118 times Last modified on Sábado, 09 Enero 2016 08:15

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    An Australian tradie who spent a month behind bars after an alleged drunk and naked rampage while on a surfing holiday in a
    conservative Indonesian province is on his way home after being deported.


    Bodhi Mani Risby-Jones, 23, had been in an Indonesian prison cell since late April after he was accused by police of drunken attacks on multiple people
    in the deeply conservative Muslim province of
    Aceh, including a fisherman who suffered serious leg injuries.


    The tradie from Queensland's Sunshine Coast was released from prison on Tuesday after he went through a restorative justice process, apologised
    for the attack and agreed to pay compensation to the
    fisherman. 

    That allowed him to avoid going to court and facing a possible
    charge of assault that could have landed him up to five years in prison.

    He spent three nights at an immigration detention centre before he was deported on Saturday. 

    Risby-Jones gave a smile and a thumbs up for the cameras as he was escorted by immigration through Soekarno-Hatta international airport for his flight home. 

    He will land in Melbourne on Sunday morning and will make his
    way back to the Sunshine Coast. 






    Bodhi Mani Risby-Jones (above) from Queensland was released from Indonesian jail on Tuesday after police claimed he went on a
    drunken rampage and injured a local fisherman







    Police claimed Risby-Jones (pictured on Saturday in Soekarno-Hatta international airport) was drunk in a province where alcohol is strictly prohibited


     'Of course I´m pretty emotional, so I´m going to feel bad about it,' Risby-Jones
    told reporters at the airport. 

    He said the fisherman's relatives forgave him and
    told him that he was a part of their family now. 

    'I'm welcome to come back and even stay at
    their house whenever I want,' he said.

    'So, that feeling of guilt is definitely much smaller that it
    was originally,' he said.

    His lawyer Idris Marbawi said the two sides agreed that Risby-Jones would pay the
    fisherman's family for hospital fees and a traditional peace ceremony. 

    The total payment was 300 million rupiah ($20,000). 

    The fisherman underwent surgery in Banda Aceh, the provincial capital, for
    broken bones and an infection in his legs.



    'Risby-Jones is the first foreigner to successfully resolve a case through restorative justice in Aceh province,' Marbawi said. 

    'He deeply regretted what happened and vowed to return to Indonesia for surfing.'

    Footage of his release on Tuesday showed Risby-Jones being escorted by officers to a bus after hugging and
    saying goodbye to several prison wardens. 

    After his release, Risby-Jones spent three nights at an immigration detention centre before he headed home on Saturday.







    Authorities said Risby-Jones (above) had come to a
    peaceful resolution with the injured fisherman through
    'restorative justice'







    Authorities said Risby-Jones (pictured before his arrest) had vowed to return to Indonesia for surfing


    'It's been a long time coming and I'm feeling amazing and super happy and
    grateful,' he said. 

    'Everyone has been very nice and accommodated me well.



    Thank you.'

    He also acknowledged the stupidity of his actions.

    'I'm very, very relieved and happy,' he said. 

    'I made a fool of myself and it was shown publicly worldwide.'

    Violent acts by foreigners are rare in Aceh, the only province in Muslim-majority Indonesia
    that practices Shariah, a concession made by the central government in 2001 as part of
    efforts to end a decades-long war for independence. 

    The sale and consumption of alcohol is forbidden in Aceh, and
    those found drunk have been caned in public.

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